congenital defect

He has a congenital heart defect.

他有先脏陷。

It is suggested that lumbosacral agenesis, a severe congenital defect, might be one of the anomalies of diabetic embryopathy.

此病例显示腰荐椎发育不全可能是母亲糖尿病所导致胚胎病变的一种，无论有无接受胰岛素治疗，此先畸形仍可能形成。

This was true whether applied to a congenital defect, such as syndactyly, or an acquired defect, such as a burn contracture.

把它们应用于诸如并指的先或是烧伤疤痕挛缩类后的修复，往往都没错。