In some instances, Siberian Huskies can exhibit what is called "snow nose" or "winter nose".This condition is called hypopigmentation in animals.

在某些情，士奇会出现所谓的“雪鼻”或“冬天的鼻子”这种情被称为“色素退”。

Oculocutaneous albinism(OCA) is a group of autosomal recessive disorders of melanin synthesis,which is characterized by congenital hypopigmentation of skin,hair and eyes.

眼肤白化病是由于黑色素合成相关基因突变导致眼、肤、毛发黑色素少或缺乏引起的一类常染色体隐形遗传疾病的总称。