Methylmalonic acidemia is an inherited metabolic disorder,which is caused by deficiency of methylmalonyl-coenzyme A mutase or its cofactor adenosylcobalamin.
A method for fluorophotometric assay of dihydrofolate reductasc (DHFR) activity by the use of fluorescence properties of dihydrofolate (DHFA) and NADPH was developed.
The THFA product of hydrogenation in common pressure has been used in enzymatic reaction and expressed the same result as that of THFA from Sigma, the cost of reduction by hydroborates is lower.
Under normal conditions, cholinergic neurons in the brain, synthesize acetylcholine from acetyl coenzyme A (acetyl CoA) and choline, in a reaction catalyzed by an enzyme choline acetyltransferase (CAT).
If you stopped consuming food, within 6 hours your body will be breaking down glycogen into glucose and fat into acetyl CoA to keep your bioloical processes at work.
We convert glucose to pyruvate through the process of glycolysis, and then we convert pyruvate to acetyl-CoA, which then gets burned, gets oxidized for energy, to produce energy through the krebs cycle.
Pyruvate enters the mitochondria, Mitochondria is like the coal furnace of your cell because it converts the Pyruvate to Acetyl-CoA, then burns that in the TCA cycle to produce a bunch of energy in the form of ATP.
丙酮酸进入线粒体,线粒体就像是你的细胞的锅炉,它把丙酮酸转换成乙酰辅酶 A,然后在三梭循环中把它烧掉,以 ATP 的形式来产生一些能量。