Recently, it has been shown that the Mitochondrial aldehyde dehydrogenase is responsible for the bioactivation of nitroglycerin prior to the release of NO, which is a strong vasodilator.

近来，有研究表明线粒体乙醛脱氢酶是体内催硝酸甘转的径，线粒体乙醛脱氢酶同时具有脱氢酶和酯酶的催活性，其酯酶活性可以通过将硝酸甘脱硝形成一氧氮，进而血管扩张。