Most are designed to target rare genetic diseases, including haemophilia B, where mutation causes problems with blood clotting.

大多数药物旨罕见的遗传疾病，包括 B 型血友病，这种疾病的突变会导致凝血问题。

To prevent complications from an existing blood or bleeding disorder, such as sickle cell disease, thalassemia, or anaemia caused by kidney disease, haemophilia, or von Willebrand disease.

预防现有血液出血性疾病的并发症，如镰状细胞病、地中海贫血由肾脏疾病、血友病血管性血友病引起的贫血。

And I guess I started modifying my behaviour somewhat because the haemophilia treatment centre I was calling in to to get my medication, you'd get various brands of it and I was frankly nervous of American brands.

我想我开始稍微改变我的行为是因为我打电话到血友病治疗中心拿药，你会得到各种品牌的药物， 坦率地说，我美国品牌感到紧张。