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Hematologic studies revealed severe hyperphosphatemia, hypocalcemia and metabolic acidosis.

液学研究显示有严重症、低钙症和代谢性酸毒。

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Tetany, epilepsy, neuro-psychiatrical symptoms, hypocalcemia, hyperphosphatemia were common clinical manifestation.There was also low level of PTH, except pseudohypoparathyroidism.

临床表现为手足抽搐、作、精神症状、钙降低、、除假性甲旁减外PTH均降低。

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With all that in mind, hyperphosphatemia can develop a few different ways.

综上所述,磷血症可以通过几种不同的方式发展。

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Osmosis-泌尿

Mild hyperphosphatemia doesn't usually cause symptoms, but severe hyperphosphatemia can make neurons more excitable.

磷血症通常不会引起症状,但重磷血症会使神经元更容易兴奋。

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Osmosis-泌尿

With long-term hyperphosphatemia, the whole kidney can eventually turn into bone, which is called nephrocalcinosis.

长期患有磷血症,整个肾脏最终可能会变成骨头,这叫做肾钙化病。

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Osmosis-泌尿

Any time a lot of cells die, that phosphate gets spilled into the bloodstream, causing hyperphosphatemia.

细胞死亡时,磷酸盐就会溢出到血液中,导致磷血症。

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Osmosis-泌尿

A final cause of hyperphosphatemia relates to the fact that most phosphate in the body is within the cells.

磷血症的最后一个原因,与体内多数磷酸盐在细胞内有关。

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Osmosis-泌尿

All right, so since, again, parathyroid hormone causes excretion of phosphate and reabsorption of calcium, then another cause of hyperphosphatemia is hypoparathyroidism, when the parathyroid glands don't produce enough parathyroid hormone in the first place.

因为甲状旁腺激素会导致磷酸盐的排泄以及钙的再吸收,那引发磷血症的另一原因就是甲状旁腺功能减退,也就是甲状旁腺首先不能产生足够的甲状旁腺激素时。

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