Method Hepatic and renal functions,and tissue biopsy were measured in rats with therapeutic,toxic and lethiferous dose treatment after a period of time.

分别测定治疗剂、中毒剂、剂组小鼠在用药一段时后的肝肾功能,并进行组织检查。

Take the experimental rats into 8 groups including 3 groups for therapeutic dose,3 groups for toxic dose and 2 groups for lethiferous dose, with 10 rats for each group and male and female for half.

将实验小鼠（幼年）分成8组，其中治疗剂3组，中毒剂3组，剂2组，每组10只，雌雄各半。