2.This heralds the start of phase two of the menstrual cycle, the proliferative, or pre-ovulatory phase, which typically lasts from days 6-14 of the cycle.
3.It's followed by the proliferative phase, during which the rising levels of ovarian estrogen make the functional layer of the endometrium thicken and sprout endometrial glands.
4.In many tissues, continuous proliferation is restricted to a subpopulation of cells, the stem cells, which undergo self-renewal, as well as differentiation, into cell types with a more restrictive proliferative potential.
5.Proliferative verrucous leukoplakia can turn into a particular type of squamous cell cancer called verrucous carcinoma, and it's also sometimes called snuff-dipper's cancer since it is more common among users of snuff and other forms of chewing tobacco.