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Fluids may increase intra-erythrocyte free water and hinder the formation of sickling.

液体治疗可胞内自水增加,止镰状变形。

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Osmosis-血液肿瘤

Repeated sickling of red blood cells damages their cell membranes and promotes premature destruction.

反复镰会损伤红细胞膜,使

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Osmosis-血液肿瘤

HbS carries oxygen perfectly well, but when it is deoxygenated, HbS changes its shape, which allows it to aggregate with other HbS proteins and form long polymers that distort the red blood cell into a crescent shape - a process called sickling.

HbS能够很好携氧,但在脱氧时,HbS会形状,从而使它HbS蛋白聚集形成长链多聚体,进而使红细胞扭曲形成新月型,该过程称为镰

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