They didn't review phenylephrine nasal sprays.

刘易斯：他们没有审查去氧肾鼻喷雾剂。

Fischman: Overall, though, if oral phenylephrine doesn't work, what should people use instead of it?

Fischman：不过，总的来说，如果口服去氧肾不起作用，人们应该用什么来代替它？

So, more products started using phenylephrine.

因此，更多的产品用去氧肾。

Fischman: But I've been taking these cold medications with phenylephrine for years and they do make me feel better.

Fischman：但是我多年来一直服用这些感冒药和去氧肾，它们确实让我感觉好多了。

Phenylephrine was actually approved in the 1970s, so it had been around a while.

去氧肾实际是在 20 世纪 70 年代获得批准的，所以它已经存在了一段时间了。

In addition to that, three trials of oral phenylephrine showed it was no better than a placebo at relieving congestion.

除此之外，三项口服去氧肾试验表明，它在缓解充血方面并不比安慰剂更好。

And the pharmacologic data side indicated that when you take oral phenylephrine, most of it is metabolized to inactive forms, so very little of the active drug—in fact, one percent, based on FDA data—actually gets into the blood.

Le：药理学数据方面表明，当您服用口服去氧肾时，大部分会被代谢为非活性形式，因此活性药物的含量极少（根据 FDA 数据，实际只有 1%）真正进入血液。