This paper texted the process to prepare metadoxine from vitamine B6 hydrochloric acid salt ,pyroglutamic acid and isoproanol.
本文以维生素B6氯化氢盐、焦谷异醇,固相合成美他多辛,纯度达96.3%。
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Research suggests that beta-amyloid proteins that accumulate in the brain of Alzheimer's patients may cause abnormal rise in extrasynaptic glutamate levels by inhibiting glutamate uptake or triggering glutamate release from glial cells.
研究表明,在老年痴呆症患者的大脑积累的β淀粉样蛋白患者能通过抑制氨酸摄取导致突触外氨酸水平异常升高或者触发胶质细胞释放氨酸盐。
In the central nervous system, nicotinic receptors are on pre-synaptic axon terminals of neurons, and when nicotine binds to them, it triggers the release of neurotransmitters like dopamine, acetylcholine, and glutamate, which is why it's considered an acetylcholine agonist.
在枢系统,烟碱受体分布于突触前的轴突末端,当尼古丁与受体结合后,会触发多巴胺、乙酰胆碱、氨酸盐等递质的释放,因此尼古丁被认为是一种乙酰胆碱受体兴奋剂。