1.The permeability of blood-brain barrier (BBB) was detected by Evans Blue (EB) leakage method, and the ultrastruncture of BBB, which contained astroglia, was observed under electron microscopy.
4.The EB solution33 gives a slightly conservative result for the tunnel settlement, while the TM solution33 overestimates the tunnel settlement slightly.
6.In this method, the shield tunnel is considered as a continuous beam, namely Timoshenko (TM) and Euler-Bernoulli (EB) beams, lying on the Pasternak foundation.
8.However, the predicted tunnel settlement curves from EB-W and TM-V are smooth and continuous, which fail to capture the discontinuous deformation at joints between rings.