When these anti-glycan IgG antibodies bind to abnormal IgA1, immune complexes are formed.

当这些糖基化的IgG与异常IgA1结合，形成免疫复合物。

And these are known as anti-glycan IgG antibodies.

这些就是糖基化的IgG。

In response, the body generates IgG antibodies that target the abnormally glycosylated residues.

在免疫应答下，机产生针对异常糖基化残基的IgG。

Meanwhile, IgG antibodies circulate for an extended period after infection;their presence usually indicates that someone was exposed and recovered.

同，IgG在感染后会循环很长间，它们的存在常表明有人被感染并康复。

Immunoassays may detect IgG antibodies, the most abundant class, and IgM antibodies, the type that's first produced in response to a new infection.

免疫以检 IgG （最丰富的一类）和 IgM （应对新感染而首先产生的）。

In these sorts of infections, IgA1 antibody production gets ramped up, leading to IgG anti-glycan formation, and immune complex deposition in the glomerular mesangium, causing inflammation.

在这些感染情况下，IgA1产生增多，导致糖基化的IgG形成，免疫复合物便沉积在肾小球系膜，产生炎症反应。

These centroblasts have a rearrangement of their immunoglobulin genes, and some of them undergo a class switch where they change from producing IgM antibodies to producing IgG or IgA antibodies.

这部分中心母细胞的免疫球蛋白基因发生了重排，其中的一些会经历Ig类别转换，从产生IgM变成产生IgG或IgA。

So combining IgG or IgM, a positive on either and looking at just 20 days or more of having illness you can see that only one test actually captured everybody, that was the test from BioPerfectus.

因此结合IgG或IgM，任何一个呈现阳性并且只看20天及以上的患病情况，你会发现只有一个试真正检出了每个病例，那就是来自BioPerfectus（江苏硕世）的试。

When the abnormal IgA1-IgG immune complexes deposit in the mesangium, the alternative complement pathway is activated, leading to the release of proinflammatory cytokines and migration of macrophages into the kidney, all of which contributes to glomerular injury.

当异常的IgA1-IgG免疫复合物沉积在系膜上，补旁路途径被激活，导致促炎因子的释放，同促进巨噬细胞向肾迁移，以上所有反应会导致肾小球的损伤。