For hemophilia A, desmopressin, also called DDAVP (1-deamino-8-D-arginine vasopressin) is helpful for patients with mild, quantitative factor VIII deficiency.
This increases circulating factor V and factor VIII levels, and " tips the scale" toward coagulation, putting them at increased risk for thrombosis, or developing blood clots.
By far the most common of these are deficiencies of factor VIII which gives rise to factor VIIIa and is stabilized by another factor called von Willebrand factor.
All right, as a quick recap, protein C and S deficiency refer to two separate hereditary hypercoagulable disorders that involve the inability to inactivate factors V and VIII in the coagulation cascade.
The word 'utopia' was coined in 1516 by Sir Thomas More - writer, saint and opponent of Henry the VIII's marriage plans - in his book of the same name.
And it's like Freddie Buick VIII for me, just in terms of its worldview and also it being like a kind of almost like sleeper agent in King's later career.
You know, the cardboard boxes and the way they were designed, and Ultima VII is black, and Ultima VIII is the fiery gate, and the paintings on them, and I just, you know...