1.Pyridazinone derivatives have considerable kinds of biological activities such as those cardiotonic,platelet aggregation inhibitory,anti-inflammatory,aldose reductase inhibitory,antifungal and so on.

1.哒嗪酮类化合物具有多种重要生物活性,根据作用机不同,可分为钙增敏剂、磷酸抑剂、环氧合抑剂等,并可用于相关治疗。

2.The synthesis of epalrestat,an aldose reductase inhibitor, was improved. The yield of its intermediate 3-carboxymethyl rhodanine was raised to 76.4%.

2.对醛搪还原抑剂依帕司他合成工艺作了改进，使中间体绕丹宁乙酸收率提高到76．4％。

3.Transketolase is the key enzyme of pentose-phophate pathway, catalyses transfer of a two-carbon fragment from a ketolase (donor substance) to an aldose (acceptor substance).

3.摘要转酮醇是磷酸戊糖途径关键，催化碳单元在酮糖（供体）和醛糖（受体）间转移。