That's where Alzheimer's patients have a buildup of toxic proteins called amyloid.

在这个部分，尔茨海默病患者积累了一种叫做粉样蛋白有毒蛋白质。

Higher deposition of amyloid goes hand-in-hand trade loss of function in Alzheimer's disease.

粉样蛋白高度沉积与尔茨海默病患者功能丧失密切相关。

It, too, targets amyloid plaques in the brain.

它针对也大脑中粉样斑。

The drugs target a protein buildup, called beta amyloid, in the brain of Alzheimer's patients.

这些药物针对尔茨海默病患者大脑中一种被称为β粉样蛋白蛋白质堆积。

Patients were also switched to inactive substances if enough amyloid cleared out.

清除了足够多粉样蛋白，患者也会改用非活性物质。

The amyloid cascade hypothesis remains the most influential explanation for how Alzheimer's develops.

粉样蛋白级联假说仍然尔茨海默病何发展最具影响力解释。

They also saw an Alzheimer's-like increase in amyloid beta plaques.

他们还发现类粉β斑块老年痴呆症样性增加。

They attack the amyloid as it clumps together.

它们聚集在一起时会攻击粉样蛋白。

Two of the newest look for fragments of these amyloid proteins in your blood.

其中两种最新检测方法在血液中寻找粉样蛋白碎片。

Having amyloid positive does not mean that you are going to get Alzheimer's disease.

粉样蛋白呈阳性并不意味着患有尔茨海默病。

Saying amyloid is a hallmark, though, is different than saying it's a cause.

然而，说粉样蛋白这种病一个特征，与说它一个病因不同。

And there are two drugs, Aduhelm and Leqembi, that are designed to clear out these amyloid clumps.

有两种药物，Aduhelm和Leqembi，专门用来清除粉样蛋白团块。

But regardless, this idea doesn't call amyloid beta into question.

但不管怎样，这种想法并未对类粉β提出质疑。

The new technique looks for protein called amyloid beta that associated with the condition. Our health correspondent James Galiga reports.

这项技术要寻找一个被称为粉状β肽蛋白质，该物质与尔兹海默病有关。以下我台医疗记者吉姆斯·加里盖报道。

So the drug both cleans up amyloid and may help with cognitive problems, at least for a little while.

这种药物既可以清除粉样蛋白，又可以帮助解决认知问题，至少在一段时间内这样。

New drugs such as Leqembi and Kisunla can slow the disease a little. The medicines remove amyloid from the brain.

像Leqembi和Kisunla这样新药可以稍微减缓疾病进展。这些药物可以清除大脑中粉样蛋白。

So these new blood tests can detect amyloid, but they don't necessarily mean you're going to get Alzheimer's.

这些新血液测试可以检测出粉样蛋白，但这并不一定说明患有尔茨海默病。

So what happens when amyloid plaques accumulate to this tipping point?

那么当粉样斑块积累到这个临界点时会发生什么呢？

Think of amyloid plaques as a lit match.

将粉样斑块想象成一根点燃火柴。

Currently, doctors have two ways to identify a buildup of amyloid beta in the brain.

目前，医生有两种方法来识别大脑中粉样蛋白积累。