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The Rochester team used a synthetic molecule – called an antisense morpholino oligonucleotide – that mimics a segment of the genetic code.

罗特小组使用合成分子——反义吗代寡意核苷酸——模仿遗传编码。

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NEJM This Week

Olizarsin is an N-acetylgalactosamine conjugated antisense oligonucleotide that targets the messenger RNA of apolipoprotein C3, which inhibits triglyceride clearance.

奥利扎辛是一种N-乙酰半乳糖胺结合反寡核苷酸,专门针对载脂蛋白C3使RNA,通过抑制甘油三酯清除发挥作。

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Research articles

So this antisense cDNA, it binds to the gene's RNA message and that basically blocks the cell from being able to produce the protein it was supposed to make.

所这个反 cDNA 与基因 RNA 结合,基本上阻止了细胞能够产生它应该制造蛋白质。

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Research articles

So researchers have figured out how to engineer these retrons, basically training them to produce very specific pieces of DNA called, get this, antisense cDNAs.

因此, 研究人员已经想出了如何设计这些逆转录素,基本上是训练它们产生非常特异性 DNA 片段,称为反 cDNA。

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Research articles

This antisense cDNA, it's like the mirror image of that code.

这个反cDNA, 就像是那个代码镜像。

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