1.Many different types have been identified most of which are autosomal dominant.

目前已经鉴定出许多不同的类型，其中大多数是常染色体显性的遗。

2.It wasn't until 2009 that 23 Me introduced autosomal DNA testing to the public.

直到 2009 年，23 Me 才向公众介绍了常染色体 DNA 检测。

3.Causes It is mostly inherited as " autosomal dominant" pattern so patients have positive family history.

原因多为常染色体显性遗，患者有阳性家族史。

4.And then the next question would be how do patients with autosomal dominant polycystic kidney disease present?

下一个问题是常染色体显性遗性多囊肾患者的表现是怎样的？

5.Mutations in BRCA-1 or BRCA-2 are both autosomal dominant mutations, which can be inherited and cause familial breast cancer.

BRCA-1BRCA-2的突变都是常染色体显性突变，可被遗并导致家族性乳腺癌。

6.Specifically, acral peeling skin syndrome is inherited in an autosomal recessive manner.

具体来说， 肢端皮肤脱皮综合征是以常染色体隐性方遗的。机翻

7.It wasn't until 2009 that 23andme introduced  autosomal DNA testing to the public.

直到 2009 年， 23andme 才向公众推出常染色体 DNA 检测。机翻

8.There are two types of familial, or congenital, protein C and S deficiency; both are inherited in an autosomal dominant manner.

家族性（先天性）蛋白CS症有两种，均为常染色体显性遗。

9.All right, as a quick recap - Marfan syndrome is an autosomal dominant genetic disorder caused by mutations in the FBN1 gene.

得！快速回顾一下：马方综合征是一种由FBN1基因突变造成的常染色体显性遗病。

10.Huntington disease is an autosomal dominant genetic disorder, which means that one affected copy of a gene is enough to cause disease.

HD是一种常染色体显性遗病，意味着可以代代相。

11.Sickle cell is an autosomal recessive disease, so a mutation in both copies of the beta-globin gene is needed to get the disease.

镰贫是一种常染色体隐性遗病，因此需要两个β-珠蛋白基因序列均突变才能获得该病。

12.The mutations are inherited in an autosomal recessive pattern, which means that you need mutated genes from both parents to get the disease.

这种变异以常染色体隐性遗方遗，即只有同时遗父母双方的突变基因才会患病。

13.Individuals with tuberous sclerosis have a mutation in either the gene TSC1 or TSC2, and these mutations have an autosomal dominant inheritance pattern.

结节性硬化症患者的TSC1或TSC2基因发生了突变，为常染色体显性遗。

14.All right, as a quick recap: alpha thalassemia is an autosomal recessive disorder caused by deletion of alpha globin genes on chromosome 16.

得！快速回顾一下：α地中海贫血是一种常染色体隐性遗病，由16号染色体上的α珠蛋白基因陷引起。

15.CF is an autosomal recessive disorder involving the CFTR gene, which stands for " cystic fibrosis transmembrane conductance regulator, " and this gene codes for the CFTR protein.

CF是一种常染色体隐形遗病，涉及CFTR基因；CFTR代表跨膜导调节基因，它编码了CFTR蛋白。

16.All right, as a quick recap, acute intermittent porphyria is an autosomal dominant disorder caused by a deficiency of the enzyme porphobilinogen deaminase in the heme synthesis pathway.

好，快速回顾一下：急性间歇性卟啉病是常染色体显性疾病，由血红素合成途径中卟胆原脱氨酶导致。

17.Now most of these gene mutations are inherited in an autosomal dominant pattern, meaning that one copy of an altered SCA gene is enough to cause the disease.

大多数的突变都以常染色体显性遗，这代表一个SCA基因突变的拷贝足以引起这种疾病。

18.CF develops when there's a mutation in the CFTR gene, but because it's autosomal recessive, you need to inherit two mutated CFTR genes, one from mom and one from dad.

CFTR基因突变时会产生CF，但它是常染色体隐形遗的；患者体内两条CFTR突变基因，一条来自母亲，另一条来自父亲。

19.As a quick recap: sickle cell disease is an autosomal recessive genetic disease where the beta-globin subunit of hemoglobin is misshapen, which causes red blood cells to sickle when deoxygenated.

好！简要回顾一下：镰状细胞病，是常染色体隐性遗病，其中血红蛋白的β-珠蛋白发生突变，脱氧情况下会导致红细胞镰变。

20.Time for a quick recap: cystic fibrosis is an autosomal recessive disorder involving the CFTR gene, which most notably causes issues with the lungs and the pancreas, but can also affect other organs.

得！快速回顾一下：囊性纤维化是一种常染色体隐形遗病，与CFTR基因有关，在肺胰腺组织中病变最为显著，但也可以影响其他器官。