Many diseases such as hypertension,diabetes mellitus,hypercholesteraemia can generate a lot of reactive oxygen species(ROS) which can cause oxidative stress.
As a result,pancreas transplantation becomes the standard treatment for type 1 diabetes mellitus that can induce an insulin-inde pendent normoglycemic state.
A report recently published in the American Journal of Epidemiology suggested that smoking increased the risk of developing non-insulin-dependent diabetes mellitus (NIDDM) by more than three times.
There are also diseases that can cause osteoporosis like Turner syndrome, hyperprolactinemia, Klinefelter syndrome, Cushing syndrome, and diabetes mellitus.
Other potential causes of renal papillary necrosis are chronic use of analgesics, like aspirin, as well as diabetes mellitus, sickle cell disease, and pyelonephritis.
Therefore, upper UTI shares a lot of the same risk factors as lower UTI: things like female sex, sexual intercourse, indwelling catheters, diabetes mellitus, and urinary tract obstruction.
In diabetes mellitus type 1, destruction of beta cells usually starts early in life, but sometimes up to 90% of the beta cells are destroyed before symptoms crop up.
A long-term consequence of chronic pancreatitis is the development of diabetes mellitus, which happens as the recurrent inflammation begins to damage the alpha and beta cells of the pancreas.