A person who always has a stick-in-the-mud attitude could also be called a downer.

一个总是墨守成规的人也可以被称为扫兴者。

Similar to the party pooper is a Debbie downer.

和“令人扫兴的人”类似的还有“Debbie downer”。

Oh, God. I shouldn't be here. -Come on. Don't be a downer.

天啊。我不该来这儿。-拜托，别那么扫兴。

In some situations, using downers can lead to death.

在一些情况下，便用镇静剂可导致死亡。

Downers are known to cause headaches, feelings of sadness and a weak pulse.

镇静剂据悉可以痛，伤感和脉搏虚弱。

You know, if you're on a downer, if you will, sometimes your body just responds accordingly.

你知道，如果你情绪落，如果你愿意，有时你的身体会做出相应的反应。

I don't want to be a downer here, but life on Earth has

也许不是明天，但我们快没时间了。

Not to be a downer but it just doesn't seem practical within the limited time frame given by 2050.

不是让人沮丧，但在到 2050 年的有限时间内，这似乎并不现实。

Most of epigenetic research has really focused on stress, anxiety, depression -- kind of a downer, kind of bad things.

大多数的表观遗传学研究都集中在压力，焦虑，抑郁上—某种负面情绪，某种不好的事情。

Some of these are like downers and I'm totally willing to admit that, but this is an absolute dance song.

其中有些会让人感到很沮丧，但这首歌绝对是一首舞蹈佳曲。

A person who always has a stick-in-the-mud attitude could also be called a downer. This means they bring people down.

一个总是墨守成规的人也可以被称为" downer" （扫兴的人）。这意味着他们总会让气氛冷场。

And the researchers found that just the act of scheduling an activity actually put kind of a downer on things.

研究人员发现，仅仅是安排活动的行为，就能让事情变得有点沮丧。

I'm- I'm making it all about me. What a downer. It's your evening. Let's make it great, man. - No. No.

我把自己弄成主角了。真是扫兴。今晚的主角是你。让今夜此生难忘吧。-没没。

Do you have another downer for us?

您还有其他让我们沮丧的事情吗？

You know, they took a lot of these downers and would sit there.

你知道，他们吃了很多这种镇静剂，然后就坐在那里。

You don't have to sound a downer alert.

- 你不必发出令人沮丧的警报。

No. No. I'm not eating with those downers!

不，不。我不才不跟 那帮晦气吃饭！

And then to have somebody else take care of them is, it's gotta be a downer.

然后让别人照顾他们，那一定是失败者。

I'm so sorry that all of my essentials are a downer, [laughing] like filled with earnest and emotion.

我很抱歉我的所有必需品都是令人沮丧的，[笑]就像充满了真诚和情感。

He thinks he's being helpful, but he's actually being critical, and he's a downer on everything.

他认为自己是在帮忙，但实际上他是在批评，而且他对一切都泼冷水。