The World Authority on Herbs, The German Commission E, reports that Bugleweed, Motherwort, and Lemon Balm are safe and efficacious for treating hyperthyroidism.
These plantes are moste efficacious in the inflaming of the braine, and are therefore much used in Confusing and Befuddlement Draughts, where the wizard is desirous of producing hot-headedness and recklessness . . .
There are two main goals in vaccine development: first the vaccine needs to be safe to administer to the general population, second the vaccine needs to be efficacious against the pathogen, for instance a virus.
So although the medication is highly efficacious if people take all of their medication, many people do not take all their medication and therefore the effectiveness of the regimen is decreased.
" I do thank you for taking the time, Pomona, " Slughorn was saying courteously, " most authorities agree that they are at their most efficacious if picked at twilight."
" It's a public health historical event that for the first time a malaria vaccine can be safely and efficacious deployed to save lives of African children" .
If a candidate vaccine makes it through all 3 phases of clinical trials and is shown to be both safe and efficacious at combating the virus, then it is approved for manufacturing and distribution to the population.
Vaccine doses that are too low may not create an efficacious immune response, whereas vaccine doses that are too high may cause unwanted side effects, so finding the right dose is really important.