But in addition to the primary sequence of DNA, in addition to the As, Ts, Cs, and Gs, there's our epigenome.

但是除了 DNA 初始序列，除了 A，T，C 和 G，还有我们表观因组。

The epigenome can be changed by the environment. And those changes pass from one generation of worms to the next.

表观因组可以被环境改变，这些改变从一代蠕传递到下一代。

Mr. Sabanayagam studies the epigenome as it relates to microgravity.

Sabanayagam研究了微重力下表组因组。

And that epigenome is constantly changing.

表观因组是不断变化。

The epigenome is kinda like Play-Doh on the genome.

表观因组有因组上橡皮泥。

After about a week the scientists take out the worms. They look for changes in the worms' epigenome.

一周后科学家将蠕取出，然后观察蠕表观因组改变。

But again, what most people don't understand is sort of a dirty little secret is how difficult it is to measure the, and to sequence the epigenome, right?

但再次强调， 大多数人不太了解一个不为人密是， 测量和测序表观因组有多么困难，对吧？

So when we're young, our epigenome is pristine, it's set with genes on and genes that  are off that maintain a cell's identity.

所以当我们年轻时，我们表观因组是完美，它设定了一些因开启而一些因关闭，以维持细胞身份。

The set of all of the chemical tags that are attached to the genome of a given cell is called the epigenome.

附着于特定细胞因组上所有化学标签集合，被称为表观因组。

Think about developing therapies that target the epigenome.

想想开发靶向表观因组疗法。

The epigenome also mediates a lifelong dialogue between genes and the environment.

表观因组还促成了因与环境之间贯穿一生对话。

So they're essentially using Evo 2 to write messages in the language of the epigenome.

所以他们本上是使用Evo 2用表观因组语言来写信息。

Right. But before we get too carried away with the possibilities, I want to touch upon something we discussed earlier: the epigenome.

对。但在我们被这些可能性冲昏头脑之前，我想谈谈我们之前讨论过事情：表观因组。

A balanced lifestyle that includes a healthy diet, exercise, and avoiding exposure to contaminants may, in the long run, create a healthy epigenome.

均衡生活方式，包括健康饮食、锻炼以及避免接触污染物，从长远来看，可能有助于形成健康表观因组。

You mentioned that Evo2 can be used to control the epigenome, that layer of control on top of DNA that influences gene expression.

你提到Evo2可以用来控制表观因组，即DNA之上一层控制层，它影响因表达。

Precisely. They demonstrated the effectiveness of this technique in a remarkably creative way. They actually programmed Evo2 to write simple Morse code messages into the epigenome.

正是如此。他们以一种非常有创意方式证明了这项技术有效性。他们实际上对Evo2进行了编程，使其能够将简单摩尔斯电码信息写入表观因组。

From its ability to predict mutations and generate new DNA sequences, to its potential for controlling the epigenome and even designing entire organisms.

从其预测突变和生成新DNA序列能力，到其控制表观因组甚至设计整个生物体潜力。

Your mother's or your father's experiences as a child or choices as adults could actually shape your own epigenome.

你母亲或父亲在童年时经历或成年后选择，实际上能塑造你自己表观因组。

Each of the approximately 200 cell types in your body has essentially the same genome, but its own distinct epigenome.

你体内大约200种不同类型细胞，虽然因组本相同，却各自拥有独特表观因组。