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Here PMN's that are marginated along the venule wall (arrow) are squeezing through the basement membrane (the process of diapedesis) and spilling out into extravascular space.

图示边静脉壁的中性粒细胞(头所示)正挤基底膜(),走到血管外。

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Osmosis-遗传

First, they damage the RBC membrane, resulting in intramedullary hemolysis, or RBC breakdown in the bone marrow; or extravascular hemolysis, when RBCs are destroyed by macrophages in the spleen.

首先,它们会细胞膜,导致髓内血(骨髓中细胞分解)或血管外血(细胞被脾脏的细胞)。

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Osmosis-消化

With extravascular hemolysis, we have macrophages eating up red blood cells more than normal and unconjugated bilirubin production is ramped up, which is conjugated by the liver and sent to the gallbladder.

血管外细胞吞细胞,较正常更多,进而加速了非结合胆素的产生,非结合胆素在肝脏转变为结合胆素,并输送至胆囊。

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