1.This paper reports the improvement on the synthesis of 5 methylisoxazol 3 formamide by Claisen condensation of diethyl oxalacetate followed by cyclization and ammonolysis.

1.讨草酸二乙酯为原料,经过克莱森缩、环、氨解反应成5甲基异唑3甲酰的改进。