In other words, at a time when the working class has turned the country on its political head, frustrated that the opportunity that once defined America is vanishing, one obvious solution is staring us in the face.
Physicians frustrated by their inability to cure the disease and fearing loss of hope in the patient too often offer aggressive treatment far beyond what is scientifically justified.
So I want to make it very clear to you, I as a teacher and I as a friend and as a native speaker of English have never once felt annoyed or frustrated with somebody asking me to repeat something.