In Giardia, proteins involved in iron-sulfur cluster assembly and protein folding appear closely related to mitochondrial homologs and localize to a relict mitosome (6,7).
In mice, widespread deletion of the tumor suppressor Phosphatase and tensin homolog (PTEN) generates hamartomatous intestinal polyps with epithelial and stromal inolement.
And there is at least one transgenic strain of mice that if you get it to overexpress, a different SIRT, SIRT6, but again, these are homologs throughout the species.