These streak ovaries can't produce sex hormones, resulting in hypogonadism and low estrogen levels.

这些条索状卵巢无法产生激，导致功能低下、雌激水平低。

Though there are different causes which result in different levels of gonadotropin hormones, they all ultimately result in hypogonadism and a deficiency in testosterone or estrogen and progesterone.

尽管青春期延迟的病因很多，会导致促激水平各不相同，但最终的结果都是功能减退以及男睾酮或女雌激酮的缺乏。

Blood tests of hormone levels can give an idea of the type of hypogonadism.

血液激水平的检测可以为功能减退的类型提供参考。

The first is primary hypogonadism which is caused by dysfunction of the gonads - for example, the gonad's receptors may not respond to gonadotropin hormones, or the gonads might not have healthy cells that are capable of producing hormone.

一是原发功能减退，由功能障碍引起，例如，受体对促激不敏感或者内没有能够产生激的健康细胞。

Some acquired causes are similar to primary hypogonadism, radiation therapy, chemotherapy, and trauma to the gonads.

有些获得因与原发功能减退症相似，也包括放疗、化疗创伤。

Some congenital causes of primary hypogonadism are genetic diseases like Klinefelter or Turner syndrome.

可引起原发功能减退的先天因包括Klinefelter综合征或Turner综合征等遗传病。

But, but it's, you know, technically the drug was made for hypogonadism, right?

但是，从技术上讲，这种药物是为治疗功能减退症而研发的，对吧？

Yeah, and as far as testosterone therapy goes, if you have a deficiency in testosterone because of hypogonadism or maybe from HIV or something like that, it's obviously going to help with that.

是的， 对于睾酮疗法来说，如果你因为功能减退症或者艾滋病等原因导致睾酮不足，那么显然这种疗法会有帮助。

Conversely, if you give the man luteinizing hormone, and all of a sudden his testosterone goes up, he has secondary hypogonadism.

相反， 如果你给这个男注射促黄体生成，而他的睾酮水平突然上升，那么他就患有继发功能减退症。

This is called hypergonadotropic (because the level of gonadotropins are high) hypogonadism (because the level of gonad or ovarian hormones is low).

由于促激水平高，而或卵巢激水平低，这被称为高促激型功能减退症。

If he still has low testosterone, you know that he has what's called primary hypogonadism, which means his testosterone is low because his testes can't make testosterone.

如果他仍然睾酮水平低下，你就知道他患有所谓的原发功能减退症，这意味着他的睾酮低是因为他的睾丸无法产生睾酮。

So, to recap: Kallmann syndrome is a type of hypogonadotropic hypogonadism where olfactory neurons and gonadotropin-releasing hormone neurons don't function normally.

Kallmann综合征是一种低促激功能减退症，其嗅觉神经元与促激释放激神经元不能发挥正常功能。

Some acquired causes of primary hypogonadism are radiation therapy, chemotherapy, and trauma to the gonads.

可引起原发功能减退症的获得因有放疗、化疗创伤。

There are two main causes of hypogonadism.

功能减退有两个主要病因。

Because of this, Kallmann syndrome is a type of hypogonadotropic hypogonadism disorder.

正因如此，Kallmann综合征是一种低促激功能减退症。

Secondary hypogonadism can be due to hypothalamus or pituitary gland dysfunction; either from an inability to produce gonadotropin-releasing hormone or luteinizing and follicle stimulating hormones, or suppression from other hormones, like prolactin or thyroid hormone.

继发功能减退症可由下丘脑或垂体功能障碍导致，既可能是促激释放激、黄体生成卵泡刺激的生成能力低下，也可能是以上激的分泌受到了其他激的抑制，例如泌乳或甲状激。

Just like in secondary hypogonadism, there's a lack of gonadotropin-releasing hormone, but the key difference is that it's not considered pathologic - instead, it's thought to be a naturally slowed rate of maturation.

与继发功能减退症类似，也存在GnRH的缺乏，但关键的区别在于这种缺乏不是病理的，而是一种正常的发育延迟。

This leads to an overproduction of luteinizing and follicle stimulating hormones, so primary hypogonadism is also called hypergonadotropic hypogonadism.

这会导致LHFSH生成过多，所以原发功能减退症也称为高促激功能减退症。

The second cause of hypogonadism is secondary hypogonadism, which is also called hypogonadotropic hypogonadism because there are low levels of luteinizing and follicle stimulating hormones.

功能减退的第二个病因是继发功能减退症，也称为低促功能减退症，因为LHFSH激水平在此病中都显著降低。