These streak ovaries can't produce sex hormones, resulting in hypogonadism and low estrogen levels.

这些条索状卵巢无法产生素，导致腺功能低、素水平低。

Though there are different causes which result in different levels of gonadotropin hormones, they all ultimately result in hypogonadism and a deficiency in testosterone or estrogen and progesterone.

尽管青春期延迟的病因很多，会导致促腺素水平各不相同，但最终的结果都是腺功能减退以及男睾酮或女素和孕酮的缺乏。

Blood tests of hormone levels can give an idea of the type of hypogonadism.

血液素水平的检测可以为腺功能减退的类型提供参考。

The first is primary hypogonadism which is caused by dysfunction of the gonads - for example, the gonad's receptors may not respond to gonadotropin hormones, or the gonads might not have healthy cells that are capable of producing hormone.

一是腺功能减退，由腺功能障碍引起，例如，腺受体对促腺素不敏感或者腺内没有能够产生素的健康细胞。

Some acquired causes are similar to primary hypogonadism, radiation therapy, chemotherapy, and trauma to the gonads.

有些获得因素与腺功能减退症相似，也包括放疗、化疗和腺创伤。

Some congenital causes of primary hypogonadism are genetic diseases like Klinefelter or Turner syndrome.

可引起腺功能减退的先天因素包括Klinefelter综合征或Turner综合征等遗传病。

But, but it's, you know, technically the drug was made for hypogonadism, right?

但是，从技术上讲，这种药物是为治疗腺功能减退症而研的，对吧？

Yeah, and as far as testosterone therapy goes, if you have a deficiency in testosterone because of hypogonadism or maybe from HIV or something like that, it's obviously going to help with that.

是的， 对于睾酮疗法来说，如果你因为腺功能减退症或者艾滋病等因导致睾酮不足，那么显然这种疗法会有帮助。

Conversely, if you give the man luteinizing hormone, and all of a sudden his testosterone goes up, he has secondary hypogonadism.

相反， 如果你给这个男注射促黄体生成素，而他的睾酮水平突然上升，那么他就患有继腺功能减退症。

This is called hypergonadotropic (because the level of gonadotropins are high) hypogonadism (because the level of gonad or ovarian hormones is low).

由于促腺素水平高，而腺或卵巢素水平低，这被称为高促腺素型腺功能减退症。

If he still has low testosterone, you know that he has what's called primary hypogonadism, which means his testosterone is low because his testes can't make testosterone.

如果他仍然睾酮水平低，你就知道他患有所谓的腺功能减退症，这意味着他的睾酮低是因为他的睾丸无法产生睾酮。

So, to recap: Kallmann syndrome is a type of hypogonadotropic hypogonadism where olfactory neurons and gonadotropin-releasing hormone neurons don't function normally.

Kallmann综合征是一种低促腺素腺功能减退症，其嗅觉神经元与促腺素释放素神经元不能挥正常功能。

Some acquired causes of primary hypogonadism are radiation therapy, chemotherapy, and trauma to the gonads.

可引起腺功能减退症的获得因素有放疗、化疗和腺创伤。

There are two main causes of hypogonadism.

腺功能减退有两个主要病因。

Because of this, Kallmann syndrome is a type of hypogonadotropic hypogonadism disorder.

正因如此，Kallmann综合征是一种低促腺素腺功能减退症。

Secondary hypogonadism can be due to hypothalamus or pituitary gland dysfunction; either from an inability to produce gonadotropin-releasing hormone or luteinizing and follicle stimulating hormones, or suppression from other hormones, like prolactin or thyroid hormone.

继腺功能减退症可由丘脑或垂体功能障碍导致，既可能是促腺素释放素、黄体生成素和卵泡刺素的生成能力低，也可能是以上素的分泌受到了其他素的抑制，例如泌乳素或甲状腺素。

Just like in secondary hypogonadism, there's a lack of gonadotropin-releasing hormone, but the key difference is that it's not considered pathologic - instead, it's thought to be a naturally slowed rate of maturation.

与继腺功能减退症类似，也存在GnRH的缺乏，但关键的区别在于这种缺乏不是病理的，而是一种正常的育延迟。

This leads to an overproduction of luteinizing and follicle stimulating hormones, so primary hypogonadism is also called hypergonadotropic hypogonadism.

这会导致LH和FSH生成过多，所以腺功能减退症也称为高促腺素腺功能减退症。

The second cause of hypogonadism is secondary hypogonadism, which is also called hypogonadotropic hypogonadism because there are low levels of luteinizing and follicle stimulating hormones.

腺功能减退的第二个病因是继腺功能减退症，也称为低促腺素腺功能减退症，因为LH和FSH素水平在此病中都显著降低。