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Antiestrogen. Selective protein kinase C (PKC) inhibitor. Induces apoptosis.

抗雌激素。选择性PKC抑制剂。诱导凋亡。

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Altenusin was reported as myosin light chain kinase inhibitor and sphingomyelinase inhibitor.TAN-420E has antitumor activity.

TAN-420E曾报道有抗肿瘤性,易氧化为Herbimycin A,后者是很草剂,并具有一定抗菌性。

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Displays cytostatic and cytotoxic activity. Inhibitor of EGFR kinase. Shows antiangiogenic activity.

显示生长抑制毒性。EGFR激酶抑制剂。有抗血管生成性。

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Novel oncogene with kinase-domain (NOK) can activate multiple mitogenic signaling pathways including the janus kinases (JAK) and signal transducer and activator of transcription proteins (STAT).

摘要NOK能激包含JAK-STAT信号通路在内多种促有丝分裂信号通路。

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Uridine-cytidine kinase (UCK) (EC 2.7.1.48) is a pyrimidine ribonucleoside kinase that catalyzes the phosphorylation of uridine and cytidine to UMP and CMP.

在本论文第一章中主要是对人类尿苷苷激酶(UCK,EC 2.7.1.48)基因进行一系列研究。

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Osmosis-肌骨

Muscle proteins like creatine kinase and myoglobin start leaking out into the bloodstream.

肌肉中的蛋白质,如肌酸酶与肌红蛋白,会漏入血液中。

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Scishow 精选系列

See, phorbols mimic the action of diacylglycerol — a fatty molecule your body uses in a number of ways, including to activate an enzyme called protein kinase C, or PKC for short.

因为佛波醇类模拟了二酰基甘油的活动,二酰基甘油这种脂肪分子在你的身体里有很多作用,它能活一种蛋白酶C,简称PKC。

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健身知识

Same goes for indirect muscle recovery markers, like creatine kinase and muscle voluntary isometric force contraction, where active cooldowns don't seem to change much of these recovery factors.

结果同样在测量间接肌肉恢复的标志物中成立,例如,肌酸酶活性和肌肉自发等长收缩力,主动冷身不会对这些恢复因素造成影响。

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Osmosis-遗传

The most common type is Non-Homologous End Joining where a protein complex called DNA protein kinase begins by binding to each end of the broken DNA.

最常见的类型是非同源末端连接:一个叫做DNA蛋白酶的蛋白质复合体首先会结合到断裂的DNA末端。

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经济学人-技

Xalkori blocks the growth of tumours caused by a mutant form of the gene which encodes a signalling molecule known as anaplastic lymphoma kinase.

Xalkori能够抑制由编码信号分子间变性淋巴瘤酶基因的突变体所导致的癌细胞的增长。

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Osmosis-肌骨

Over time, cellular proteins like creatine kinase, or CK, start escaping the damaged cell and calcium starts to enter the cell, and this ultimately leads to cell death.

时间一长,如肌酸酶(CK)等细胞蛋白开损细胞中逸出,而钙离子开进入细胞,这最终造成细胞死亡。

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健身知识

Time to exhaustion, ratings of perceived exertion, heart rate, and fatigue factors, such as serum lactate and creatine kinase levels.

运动至力竭时间,感知体力的评分,心率,疲劳因素,如血清乳酸和肌酸酶的水平。

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Osmosis-肌骨

When Rhabdomyolysis develops, the laboratory workup can show elevated levels of creatine kinase and myoglobin, while urinalysis can show tea-colored urine due to high levels of myoglobin.

发生横纹肌溶解时,实验室检查可发现肌酸酶和肌红蛋白水平升高,尿检可见由肌红蛋白升高导致的茶色尿。

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名人73个快问快答

Did you know that molecular dynamics can be used to study proteins, enzymes and kinases?

您知道分子动力学可用于研究蛋白质、酶和酶吗?

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博兹曼学——生物

This whole thing is called a protein kinase.

整个过程称为蛋白酶。

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跟着小姐姐看技

At this point in the episode I was expecting to be talking about cancer vaccines or kinase  inhibitors or immunotherapy - something that I keep hearing about in the news.

在这一集的这一点上,我本以为会谈论癌症疫苗或酶抑制剂或免疫疗法——我不断在新闻中听到这些内容。

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Real Survival Stories

After running tests, the doctors explain that her blood contains shockingly high levels of creatine kinase, an enzyme that is generated in response to muscle breakdown.

在进行了一系列检查后, 医生解释说, 她的血液中含有一种令人震惊的高水平肌酸酶,这是一种肌肉分解时产生的酶。

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医学之光:人类与疾病的斗争

Laboratory results on hospital days 3 and 5 (illness days 7 and 9) reflected leukopenia, mild thrombocytopenia, and elevated levels of creatine kinase (Table 1).

住院第 3 天和第 5 天(发病第 7 天和第 9 天)的实验室结果反映出白细胞减少、轻度血小板减少和肌酸酶水平升高(表 1)。

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NEJM This Week

Over time, persistently high aminotransferase and creatine kinase levels raised suspicion for a muscle rather than liver disorder.

随着时间推移,持续升高的转氨酶和肌酸酶水平引发了对其为肌肉而非肝脏疾病的怀疑。

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Fast Facts Non-Small-Cell Lung Cancer

Mechanisms of AR to MET-TKIs include MET kinase domain mutations and high levels of amplification of the MET exon 14-mutant allele in up to 35% of cases.

AR 至 MET-TKI 的机制包括 MET 酶结构域突变和高达 35% 的病例中 MET 外显子 14 突变等位基因的高水平扩增。

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Boost Your Biology with Lucas Aoun

So the kinase enzymes inhibit pyruvate dehydrogenase from working.

所以酶酶会抑制丙酮酸脱氢酶的活性。

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Real Survival Stories

Right now, Karen is showing creatine kinase levels of 55,000, 50 times that of a marathon runner following a race.

目前, 凯伦的肌酸酶水平为55,000,是马拉松选手赛后水平的50倍。

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Fast Facts Non-Small-Cell Lung Cancer

ROS1 rearrangement ROS1 rearrangements lead to fusions of the ROS1 tyrosine kinase domain (on chromosome 6) with partner genes, usually on other chromosomes, and occur in approximately 2% of NSCLCs.

ROS1 重排 ROS1 重排导致 ROS1 酪氨酸酶结构域(位于 6 号染色体上)与伴侣基因(通常位于其他染色体上)融合,发生在大约 2% 的 NSCLC 中。

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博兹曼学——生物

And those secondary messengers in this case are going to target something called the protein kinase.

在这种情况下,这些次级信使将会作用于一种称为蛋白酶的目标。

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NEJM This Week

Despite TB treatment, she continued to have mild proximal muscle weakness and elevated creatine kinase levels.

尽管接了结核病治疗,她仍持续出现轻度近端肌无力及肌酸酶水平升高。

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