When I took metformin, supposedly to live longer?

当我服双胍时， 据说可以活得更久？

If you have diabetes, you see the endocrinologist, you get metformin.

患有糖尿病，会去看内分泌科医生，然后会得到双胍。

And it lowers blood sugar just about as well as metformin does.

并且它降低血糖的效几乎和双胍一样好。

I've decided to stay away from metformin and rapamycin.

我决定远离双胍和雷帕霉素。

I'll just be very direct and say I do not take metformin.

我会非常直接地说我不服双胍。

He has a history of hypertension and diabetes that have been well controlled with hydrochlorothiazide, Losartan, and metformin.

他有高血压和糖尿病史，通过使氢氯噻、氯沙坦和双胍得到了良好控制。

You can take metformin or an SGLT2 inhibitor or a GLP-1 agonist and you will directly impact those things.

可以服双胍、SGLT2抑制剂或GLP-1受体激动剂，这些药物将直接作于那些目标。

My rule of thumb is the worse your gut microbiome to start, the more metformin and GLP-1s can help.

我的经验法则是，肠道微生物群越差，双胍和胰高血糖素样肽-1（GLP-1）药物的帮助就越大。

The fact that people with  diabetes who were taking metformin died less than people WITHOUT diabetes is HUGE.

服双胍的糖尿病患者的死亡率比没有糖尿病的患者要少，这一事实是巨大的。

They're looking back at what happened, they weren't able to test whether metformin CAUSED it to happen.

他们正在回顾发生的事情，但无法测试双胍是否导致了这种情况的发生。

And second, the only people taking metformin in this study were people with diabetes.

其次，这项研究中唯一服双胍的人是糖尿病患者。

Increase if growth hormone increases high dose metformin IGF one does not tend to increase, especially if insulin decreases.

生长激素增加， 高剂量双胍的情况下， 类胰岛素生长因子-1通常不会增加，特别是胰岛素水平下降的话。

We have research on this going back decades to  before metformin was first approved.

我们对此的研究可以追溯到双胍首次获得批准之前的几十年。

In people with diabetes, these blood sugar levels  can get too high and metformin helps control that.

对于糖尿病患者，血糖水平可能会过高，双胍有助于控制这种情况。

Other studies show metformin does seem  to have anti-aging effects in healthy mice and worms.

其他研究表明双胍似乎确实对健康小鼠和蠕虫具有抗衰老作。

I personally don't take metformin, that's how my calculation came out.

我个人不服双胍，这就是我的计算结。

So if you're interested in things like rapamycin, metformin, and whether or not fasting can improve longevity, we get into that as well.

因此， 若对雷帕霉素、双胍等药物，以及间歇性禁食是否能延长寿命感兴趣，我们也会深入探讨这些话题。

The people with diabetes who weren't taking metformin had double the mortality - the number of  deaths - than the people without diabetes.

未服双胍的糖尿病患者的死亡率（死亡人数）是非糖尿病患者的两倍。

But metformin isn't the only option being studied.

但双胍并不是正在研究的唯一选择。

Which is interesting… But to know for sure whether metformin can actually delay aging in most people, we need more research.

这很有趣… … 但要确定双胍是否真的能延缓大多数人的衰老，我们需要更多的研究。