As we age, some stretches of DNA get more methylated, and others less.

随着年龄的增长，一些DNA片段的甲基化程度会上升，而另一些则会下降。

If the paternal imprinting center is mutated, the region gets methylated and those genes get turned off, meaning that both the maternal and paternal genes are silenced.

如果父源印记中，基将被甲基化沉默，导致母源和父源基都处于沉默状态。

Newborns whose mothers suffered from depression while they were pregnant are known to have more highly methylated glucocorticoid-receptor genes than others.

新生儿的母亲若是在怀孕期间出现抑郁症状，他们糖皮质激素受体基的甲基化程度会比其他新生儿更高。

The consequence is to inactivate the gene being methylated.

甲基化作用将使甲基化的基失去活性。

If both copies of chromosome 15 were derived from the mother, that means all the prader willi genes are methylated and silenced, since there's no unsilenced paternal genes.

如果15号染色体的两条同源染色体都来自母方，着所有的普拉德-威利基都被甲基化沉默，根本没有父源基的表达。

Translocations can disrupt SNRNP and move the small nucleolar RNA genes away from their imprinting center, causing them to get methylated and turned off.

SNRNP基易位会破坏小核内核糖核蛋白（SNRPN），并将核仁小RNA基移出印记中，导致这些基的甲基化沉默。

So anytime I had a client who presented these symptoms, with tributavines, didn't work, I'd switch to methylated, and I'd say 50% of the time it did the trick.

此，每当遇到表现出这些症状的客户，在使用普通叶酸无效时， 我会改用活性叶酸，大约有一半的情况， 问题这样解决了。

In one famous experiment, when mother rats weren't attentive enough to their pups, genes in the babies that helped them manage stress were methylated and turned off.

在一个着名实验中， 当母鼠对幼崽的照顾不够周到时，幼崽体内帮助它们应对压力的基会被甲基化并关闭。

Take that with a methylated multivitamin and take that with an omega-3 fatty acid, and you have all the bases covered first thing in the morning.

早上第一件事是服用甲基化复合维生素和Omega-3脂肪酸，这样你涵盖了所有基础。

But if you don't methylate that metal out of your body and you keep eating that same kind of fish, I mean, nobody got mercury poisoning from a single piece of tuna fish.

但如果你不能将体内的金属甲基化排出， 并且继续吃同一种鱼，我是说， 没有人会为吃了一块金枪鱼汞中毒的。

I once had a functional medicine practitioner that I worked with recommend to my client methylated B vitamins.

我曾与一位功能医学从业者合作，他建议我的客户服用甲基化B族维生素。