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In the fields of epigenetics and epigenomics, DNA methylation has been drawn a special attention because of its close correlation to human development and carcinogenesis.

DNA甲基化已经成为传学基因组学的重要研究内容,人基因组计划的最终目标出人基因组中甲基化可变位点图谱。

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It is ascertained that the PABA may be N-dimethylated using dimethyl sulfate as a methylation agent.

确定以硫酸二甲酯为N——甲基化剂,对对氨基苯甲酸PABA进行N——二甲基化.

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经济学人-科技

Nor was the mother's own methylation affected by violence towards her.

而且她们本身基因的甲基化与否否遭到家庭暴力无关。

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科学60秒-科学美国人 2023年3月合集

DNA methylation, which are the methyl group tags on your DNA..., serve as biomarkers of either things that have already happened in your DNA or potentially even can change the function in terms of how a gene is transcribed.

DNA 甲基化——你 DNA 上的甲基标签——种生物标志物,要么标记已经发生在 DNA 上的事情,要么标记甚至有可能改变基因转录功能的东西。

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科学60秒-科学美国人 2024年3月合集

Studies of the Dutch Hunger Winter actually show that people who were exposed to famine during gestation had differences in DNA methylation 60 years later, compared with siblings who were born later on.

对《荷兰饥饿严冬》的表明,相比饥荒后出生的兄弟姐妹,在母亲妊娠期处在饥荒中的人 DNA 甲基化在 60 年后存在差异。

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Osmosis-遗

A third way to get Prader-Willi syndrome, is a mutation in the imprinting center, which is a sequence of DNA near the Prader-Willi genes that directs imprinting via sex-specific methylation.

第三种导致普拉德-威利综合征的原因印记中心的突变;印记中心临近普拉德-威利基因的DNA序列,通过性别特异的甲基化介导印记。

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VOA Standard 2013年10月合集

Horvath and his colleagues gleaned information from 8,000 samples to chart methylation in healthy and diseased organs, tissues and cells, from fetuses to centenarians.

霍瓦特及其同事从8000个样本中收集了信息,用于绘制健康和有病器官、组织和细胞中的甲基化情况,涉及胎儿到百岁老人之间各年龄的人。

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简单心理学

In 2021, researchers published a study that looked at methylation of DNA in human and primate brains.

2021年,人员发表了一项了人类和灵长类大脑中DNA的甲基化

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科学60秒-科学美国人 2020年11月合集

Wang worked in Trey Ideker's lab, where they study changing patterns of DNA methylation in humans.

王在特雷·艾德克的实验室工作,他们在那里人类DNA甲基化模式的变化。

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科学60秒-科学美国人 2023年3月合集

I would argue DNA methylation is also dynamic and not fatalistic either.

我会认为 DNA 甲基化动态变化的,并非宿命性的。

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VOA Standard 2013年10月合集

Methylation is a naturally occurring epigenetic - or gene altering - process that chemically modifies the DNA and is critical in the development of every organism.

甲基化一种自然出现的基因改变过程,能在化学方面修改DNA,对每种生物体的发育来说至关重要。

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科学60秒-科学美国人 2024年3月合集

Epigenetics. It's basically the set of processes that turn parts of the genome on or off. And this normally happens is through something called DNA methylation.

答案表观遗学。它一系列可以打开或关闭部分基因组的过程,通常通过一种叫做DNA甲基化的方式发生。

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简单心理学

If those genes are being fine tuned through methylation, our brains growth and evolution might depend more on the serebelum than we thought.

如果这些基因通过甲基化得到了微调,那么我们大脑的生长和进化可能比我们想象的更依赖于血清。

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经济学人-科技

In the case of stress, previous studies have suggested that methylation of the gene which encodes glucocorticoid receptors is important.

以往的表明,当母亲压力过大时,负责为糖皮质激素受体编码的基因的甲基化具有重要意义。

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科学60秒-科学美国人 2020年11月合集

The same process happens in dogs-and published reports existed from other labs about methylation patterns in dogs changing over time.

同样的过程发生在狗狗身上,而且其他实验室发表了有关狗甲基化模式随时间而变化的报告。

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Osmosis-遗

Sometimes that methylation occurs on the paternal chromosome even when there's no imprinting center defect, and that's called an epimutation.

有时即使印记中心没有突变,父源染色体可以发生甲基化,这一过程称为表观突变。

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简单心理学

They found different levels of methylation between humans and primates, but the difference was bigger in samples taken from the cerebellum than from the neocortex.

人类和灵长类动物之间的甲基化程度不同,但小脑样本的甲基化程度差异更大,而新皮层样本的甲基化程度差异更大。

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Osmosis-遗

Normally the paternal grandmother's methylation, after being passed to the father, would be erased when the father's making sperm.

正常情况下,奶奶的甲基化基因遗给父亲后,在父亲产生精子时会发生去甲基化。

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经济学人-科技

Dr Tung and Dr Gilad found that methylation patterns were systematically different in high- and low-ranking animals.

博士东和吉拉德发现甲基模式在地位高级和地位低级的动物之间不一样的,且这种不一样系统性的不一样。

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经济学人-科技

The most common mechanism is methylation.

最常见的方式通过甲基化作用来完成。

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经济学人-科技

And in rats, such methylation makes young animals especially sensitive to stress, and also fearful of novelty.

而老鼠试验表明,这样的甲基化过程让幼小动物对压力尤其敏感,对新鲜事物感到恐惧。

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经济学人-科技

In infants, the level of glucocorticoid-receptor methylation is correlated with the release, in response to stress, of higher-than-normal amounts of stress hormones.

胎儿糖皮质激素的甲基化程度与人体抑郁时分泌过多的压力激素有关。

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