6.This neuronal loss is frequently accompanied with astrocytosis,gliosis and specific neuropathologic markers,such as Lewy body in Parkinson's disease.
7.The mechanisms of cognitive impairment caused by carotid diseases are associated with hypoperfusion, leukodystrophy, silent or lacunar infarcts and neuronal degeneration.
9.Conclusion:Quantitative study of MRI and 1H MRS is essential for determination of normal myelinization and neuronal integrity and age-related biochemical changes in the brain.