The complex can translocate from cytoplasm to cell nucleus,where PDX-1 could display its biological functions.
多种细胞受体与配体结合后通过不同
信号转导通路参与PDX-1
表达和生物学活性
调控。
It receives dopaminergic innervations from ventral tegment area and SNc, and noradrenergic and serotonergic innervations from the locus ceruleus (LC) and dorsal raphe nucleus (DRN), respectively.
腹
侧前额叶皮层主要接受来自腹侧被盖区(ventral tegmental area,VTA)和SNc
DA能神经纤维投射,以及来自蓝斑
去甲肾上腺素(noradrenaline,NA)能和中缝背核
5-HT能神经纤维投射。
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