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Objective To observe the effects of the fracture healing stimulin, a fracture healing increasing drug from staphylococcus aurous on osteoblasts in vitro .

目的观察骨折愈培养成骨细胞的作用。

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Osmosis-肌骨

Other benign tumors are osteoblastomas and osteoid osteomas, both of which arise from osteoblasts.

其他良性肿瘤包括成骨瘤、骨样骨瘤,两者均起源于成骨

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Crash Course 解剖生理学篇

So an osteoblast in your bone becomes an osteocyte — ditto for chondroblasts becoming chondrocytes.

所以你骨骼中的成骨就变成了一个骨。——软骨成为软骨也是如此。

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Osmosis-肌骨

These collagen fibers are the framework for the osteoblasts' work.

这些胶原纤维为成骨的工作构建了框架。

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Osmosis-肌骨

Osteosarcomas arise from osteoblasts of different sizes - called pleomorphic - and these cells produce too much osteoid tissue.

骨肉瘤起源于大小不同的成骨(多形性);这些会产生过多的类骨组织。

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Osmosis-肌骨

Osteoblasts then deposit calcium and phosphate crystals into the framework.

成骨会往这个框架内积聚钙和磷酸盐结晶。

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Osmosis-肌骨

Now, for bones to grow and develop properly, special bone cells, called osteoblasts, are hard at work.

在骨正常的生长发育过程中,有一种特殊的骨,成骨,起了至关重要的作用。

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Osmosis-肌骨

To build bone, osteoblasts secrete osteoid, which is an organic matrix made of type 1 collagen.

在构建骨的过程中,成骨泌类骨质,它是一种由1型胶原组成的有机质。

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Osteoclasts break down the unneeded mineral lattice using acids and enzymes so that osteoblasts can then add more material.

破骨以酸和酵素酶 将无用的矿物晶格拆解这样就可以提供 更多原料给造骨

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Osmosis-肌骨

Bone mineralization is dependent on an enzyme called alkaline phosphatase - which increases in response to osteoblast activity.

骨的矿化依赖碱性磷酸酶;碱性磷酸酶响应成骨活性而增加。

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Osmosis-肌骨

This means that osteoblasts don't have enough calcium and phosphate to deposit into the organic matrix.

这意味着成骨没有足够的钙和磷可以沉积到骨有机质中。

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Crash Course 解剖生理学篇

But before they auto-terminate, they use the hormone hotline to call over the osteoblasts, who come in and begin rebuilding the bone.

但是在它们自动终止之前,它们使用激素热线呼叫成骨,成骨进来开始重建骨骼。

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Osmosis-肌骨

Hydrochlorothiazide boosts calcium retention in the kidney and directly stimulates osteoblast differentiation, therefore decreasing mineral bone loss.

氢氯噻嗪促进肾脏中钙的保留且直接刺激造骨化,因此减少骨质流失。

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Crash Course 解剖生理学篇

They're like the construction foremen of your bones, passing along commands to your skeleton's two main workhorses: the osteoblasts and the osteoclasts.

它们就像你骨骼的建筑工头,将命令传递给你骨骼的两个主要主力:成骨和破骨

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Osmosis-肌骨

Eventually osteoblasts get activated and a process called ossification will start, which is when the fibrous tissue turns to bone.

成骨活化,骨化过程启动,纤维组织最终转化为骨组织。

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Crash Course 解剖生理学篇

Likewise, osteoblasts are the blast cells of bone tissue, and the matrix they lay down is the nexus of calcium carbonate that forms your bone.

同样地,成骨是骨组织的成骨,它们形成的基质是形成骨骼的碳酸钙的结合体。

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Crash Course 解剖生理学篇

When osteoblasts come in, they secrete a glue-like cocktail of collagen, as well as enzymes that absorb calcium, phosphate, and other minerals from the blood.

当成骨进入时,它们泌胶原蛋白以及从血液中吸收钙、磷酸盐和其他矿物质的酶。

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Crash Course 解剖生理学篇

And finally we got an introduction to the process of bone remodeling, which is carried out by crews of osteocytes, osteoblasts, and osteoclasts.

,我们得到了骨骼重塑过程的介绍,这是由骨、成骨和破骨团队进行的。

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Osmosis-肌骨

Now, even though parathyroid hormone stimulates bone resorption, it's been found that intermittent injections with teriparatide activates osteoblasts more than osteoclasts, therefore increasing bone formation.

其实,即使甲状旁腺激素刺激骨吸收,研究发现间歇性注射特立帕肽激活了更多造骨而非破骨,从而增强骨生长。

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Osmosis-肌骨

Ok, now, when osteoclasts break down bone faster than the osteoblasts can rebuild it, it results in the lowering of the bone mass and eventually in osteoporosis.

那么,当破骨解骨骼的速度比造骨重建骨骼更快时,骨量就会减少,最终导致骨质疏松。

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Crash Course 解剖生理学篇

So while your osteoblasts are the bone-makers, your osteoclasts are the bone-breakers — which is a kind of violent image. Maybe think of them as like a bone-breaker-downer.

所以当你的成骨是骨骼制造者,你的破骨是骨骼破坏者——这是一种暴力的形象。也许可以把它们想象成一个碎骨剂。

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