1.These collagen fibers are the framework for the osteoblasts' work.

这些胶原纤维为成骨的工作构架。

2.Now, for bones to grow and develop properly, special bone cells, called osteoblasts, are hard at work.

在骨正常的生长发育过程中，有一种特殊的骨，成骨，起至关重要的作用。

3.Osteoclasts break down the unneeded mineral lattice using acids and enzymes so that osteoblasts can then add more material.

破骨以酸和酵素酶 将无用的矿物晶格拆解这样就可以提供 更多原料给造骨。

4.To build bone, osteoblasts secrete osteoid, which is an organic matrix made of type 1 collagen.

在构骨的过程中，成骨分泌类骨质，它是一种由1型胶原组成的有质。

5.So an osteoblast in your bone becomes an osteocyte — ditto for chondroblasts becoming chondrocytes.

所以你骨骼中的成骨就变成一个骨。——软骨母成为软骨也是如此。

6.Other benign tumors are osteoblastomas and osteoid osteomas, both of which arise from osteoblasts.

其他良性肿瘤包括成骨瘤、骨样骨瘤，两者均起源于成骨。

7.Hydrochlorothiazide boosts calcium retention in the kidney and directly stimulates osteoblast differentiation, therefore decreasing mineral bone loss.

氢氯噻嗪促进肾脏中钙的保留且直接刺激造骨分化，因此减少骨质流失。

8.Osteoblasts then deposit calcium and phosphate crystals into the framework.

之后成骨往这个架内积聚钙和磷酸盐结晶。

9.This means that osteoblasts don't have enough calcium and phosphate to deposit into the organic matrix.

这意味着成骨没有足够的钙和磷可以沉积到骨有质中。

10.But before they auto-terminate, they use the hormone hotline to call over the osteoblasts, who come in and begin rebuilding the bone.

但是在它们自动终止之前，它们使用激素热线呼叫成骨，成骨进来开始重骨骼。

11.Osteosarcomas arise from osteoblasts of different sizes - called pleomorphic - and these cells produce too much osteoid tissue.

骨肉瘤起源于大小不同的成骨（多形性）；这些产生过多的类骨组织。

12.Bone mineralization is dependent on an enzyme called alkaline phosphatase - which increases in response to osteoblast activity.

骨的矿化依赖碱性磷酸酶；碱性磷酸酶响应成骨活性而增加。

13.They're like the construction foremen of your bones, passing along commands to your skeleton's two main workhorses: the osteoblasts and the osteoclasts.

它们就像你骨骼的筑工头，将命令传递给你骨骼的两个主要主力：成骨和破骨。

14.Eventually osteoblasts get activated and a process called ossification will start, which is when the fibrous tissue turns to bone.

最后成骨活化，骨化过程启动，纤维组织最终转化为骨组织。

15.Likewise, osteoblasts are the blast cells of bone tissue, and the matrix they lay down is the nexus of calcium carbonate that forms your bone.

同样地，成骨是骨组织的成骨，它们形成的基质是形成骨骼的碳酸钙的结合体。

16.Now, even though parathyroid hormone stimulates bone resorption, it's been found that intermittent injections with teriparatide activates osteoblasts more than osteoclasts, therefore increasing bone formation.

其实，即使甲状旁腺激素刺激骨吸收，研究发现间歇性注射特立帕肽激活更多造骨而非破骨，从而增强骨生长。

17.When osteoblasts come in, they secrete a glue-like cocktail of collagen, as well as enzymes that absorb calcium, phosphate, and other minerals from the blood.

当成骨进入时，它们分泌胶原蛋白以及从血液中吸收钙、磷酸盐和其他矿物质的酶。

18.Importantly, ectopic expression of c-Fos in H2-c-fosLTR transgenic mice drives osteoblast and chondrocyte proliferation resulting in osteosarcoma and chondrogenic sarcoma.

重要的是，H2-c-fosLTR转基因小鼠中c-Fos的异位表达驱动成骨和软骨的增殖，导致成骨肉瘤和软骨肉瘤的形成。机翻

19.And finally we got an introduction to the process of bone remodeling, which is carried out by crews of osteocytes, osteoblasts, and osteoclasts.

最后，我们得到骨骼重塑过程的介绍，这是由骨、成骨和破骨团队进行的。

20.With senile osteoporosis, on the other hand, it's believed that osteoblasts just gradually lose the ability to form bone, while the osteoclasts keep doing their thing unabated.

另一方面，老年性骨质疏松被认为是由于造骨逐渐失去造骨的能力，同时破骨持续工作，活力不减。