Most people with mild hypophosphatemia have no symptoms, but severe hypophosphatemia can cause muscle weakness, weak bones or osteomalacia, and rhabdomyolysis which is a type of kidney damage due to muscle breakdown, as well as an altered mental status.

大多数轻度低磷血症患者无症状，但严重的低磷血症引起肉无力、质疏松或软化、溶解症（一种由肉损伤造成的肾脏损伤）以及精神状态改变。

For example, rickets or osteomalacia can occur in chronic liver disease, due to the liver's inability to turn inactive vitamin D into 25-hydroxy-vitamin D.

例如，慢性肝病患者可能患佝偻病或软化症，这是因为肝脏无法将无活性的维生素D转化为25-羟维生素D。

Treatment for both rickets and osteomalacia typically involves oral vitamin D supplementation and treating the underlying cause which could be any condition affecting the organs responsible for vitamin D activation.

佝偻病软化症的治疗一般包括口服补充维生素D以及治疗潜在病因，即任何可能影响机体活化维生素D的情况。

Now, X-ray imaging of rickets and osteomalacia might show signs of decreased bone mineral density or osteopenia.

佝偻病软化症的X线检查，可能有矿物质密度减低即质缺乏的征象。

Alright, as a quick recap, rickets, and osteomalacia are conditions in which bone softening occurs due to a mineral deficiency or lack of vitamin D.

好！快速回顾一下：佝偻病软化症即由缺乏维生素D引起的质软化。

For osteomalacia and rickets, the key symptoms are diffuse bone and joint pain, proximal muscle weakness, bone fragility, and increased risk of fractures with minimal trauma.

软化症佝偻病的共同症状包括弥漫性关节痛、近端肉无力、脆，及轻微外力即可引起折。

Ok, now vitamin D deficiency is the most common cause of both rickets and osteomalacia.

好，维生素D缺乏是引起佝偻病、软化症最常见的原因。

With both rickets and osteomalacia, symptoms include diffuse bone and joint pain, proximal muscle weakness, bone fragility, and increased risk of fractures with minimal trauma.

患佝偻病或软化症时，有弥漫性或关节疼痛、近端肉无力、脆，以及即使是轻微碰撞也可能导致折。

If we zoom into a cross-section of an osteoporotic bone, it will show normal cells with normal mineralization, which differentiates it from osteomalacia where there's lack of mineralization.

如果我们放大来看质疏松的骼截面，就能看到正常矿化的细胞，这让它区别于缺少质矿化的软化症。