A mutant, TS-N-121 was obtained by mutation and plate screening from a parent strain Mycobacterium fortuitum MF2 , which could transform sterol into androstanedione as the main product.
从雄甾二酮的转化
菌偶发分枝杆菌MF2出发,经

变结合平板筛选,
得一株主要转化

酮的突变株TS-N-121。
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Benjamin Nettersheim, a geobiologist at the University of Bremen in Germany, Jochen Brocks, a palaeobiogeochemist at the Australian National University in Canberra, and their colleagues decided to focus on short-lived molecules that modern eukaryotes make while synthesizing sterols.
德国不莱梅大学

生
学家本杰明·内特谢姆、澳大利亚国立大学堪培拉分校
古生

化学家约翰·布洛克斯及其同事决定将重点放在现代真核生
合成类
醇时产生
短寿命分子上。