Hyperplasia of synovium leads to formation of pannus which destroys cartilage and bone in the affected joint.
大量增生的滑膜组致血管的生成,渐侵蚀软骨,造成关节的损伤。
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As " type A" cells in the synovium attempt to remove the debris, immune cells like lymphocytes and macrophages are recruited into the synovial membrane, which produces proinflammatory cytokines that ultimately cause inflammation of the synovium as well, called synovitis.
滑膜上的A型力清除这些碎片的同时,免疫(如淋巴、巨噬)也被募集进入滑膜,产生炎症因子,最终导致滑膜炎。
The synovium's composed of loose connective tissue, blood vessels, lymphatic vessels, and on the surface—" Type A" cells that clear cellular debris and " Type B" cells that produce components of synovial fluid, which helps lubricate the two articular surfaces.
滑膜由松散结缔织、血管、淋巴管;在滑膜表面,A型清理碎屑,B型产生滑液分,滑液能够润滑两块关节的表面。