1.Objective:To study the antifungal activity of triazole alcohols by introduction of cyclopropyl as side chain.

1.研究具有环丙基三唑醇类化合物抗真活性。

2.OBJECTIVE: To introduce the research and development of systematic antifungal drugs such as imidazole,triazole,allylamine,antibiotic etc.and the marketing trend.

2.介绍咪唑类、三唑类、烯丙胺类、抗生素类等全身用抗真药研发进展市场应用趋势。

3.Tebuconazole, which belongs to triazole fungicide, can inhibit the biosynthesis of ergosterin in fungi.There are three main commercial products: Raxil, Folicur and Horizon.

3.戊唑醇属三唑类杀剂,可抑制真中麦角甾醇生物合成,主要商品有:莠、富力库、三种。

4.By the reaction of 2 aryl 5 mercapto 1,3,4 triazoles with alkyl dihalide in presence of dilute base, ten new title compounds had been prepared.

4.以2-芳基-5-巯基-1，3，4-三唑为原料，在稀碱存在下与二卤代烷反应合成了10个新标题化合物。

5.Nitro 1,2,4 triazole 5 one(NTO)can be obtained by nitrating 1,2,4 triazole 3 one (TO) under different conditions,and nitrobenzyl derivatives of TO are prepared as well.

5.研究了1，2，4三唑酮3（TO）衍生物合成，果表明TO在多种硝化条件下均可制得3硝基1，2，4三唑酮5（NTO），同时还合成了TO二取代硝基苯衍生物。