We just don't need them to be overactive or underactive, you know.

我们不需它们迟钝，明白吗。

Cracked heels could be a sign of underactive thyroids.

脚后跟干裂可能是甲状腺功能低下的征兆。

And so it can make anxiety worse if it affects the genes that express cortisol production by making it overactive or underactive.

因此，如果它影响了表皮质醇生成的基因，使其度性不足，可能会加剧焦虑。

They are either overactive or underactive, depending on what symptoms we're looking at, but they've got a malfunctioning brain that is causing the experience of depression.

它们么度， 么不足，这取决我们观察的症状是什么，但他们的大脑功能出现了故障， 导致了抑郁体验。

It's just the same thing as when the thyroid's underactive, you go and take thyroid replacement.

这就像甲状腺功能低下时，你去服用甲状腺替代药物一样。