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Finally, we gained four esterifiable quinolone analogues (compounds 22 to 25) by modifying the structures of compound 3, 14 and 16 on 3 position.

同时利用所合成的化合物3,14,16为模板,对它们的3位羧基进化反合成4诺酮类化合物:化合物22—25。

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Quinolone is known as broad antibacterial spectrum,high potency,no crossing drugresistance with other antibacterial drugs,and easy and low cost to administer.

诺酮类药物具有抗菌谱广、抗菌活性强、给药方便,与常用抗菌药物无交叉耐药性、价格低等特点。

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Osmosis-微生物

Treatment of Legionnaires' disease is done with macrolides such as azithromycin, or with fluoroquinolones such as levofloxacin.

退伍军人病的治疗药物包括:大环内酯类抗生素,如阿奇霉素,或诺酮,如左氧沙星。

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Osmosis-微生物

Legionnaires' disease is treated with macrolides and fluoroquinolones, and Pontiac fever resolves spontaneously and does not require treatment.

退伍军人病可通过大环内酯类抗生素诺酮治疗;庞蒂亚热会自好转,无需特殊治疗。

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Osmosis-微生物

It's a multidrug resistant bacteria, and it can be treated with cephalosporins, aminoglycosides, fluoroquinolones, and carbapenems in case of beta-lactamase production; only with carbapenems in case of ESBL production; and with colistin, tigecycline or fosfomycin in case of carbapenemases production.

雷伯杆菌也是一种多重耐药菌,如果产生β-内酰胺酶,可以用头孢菌素、氨基糖苷类、诺酮类以及碳青霉烯类药物治疗;如果产生ESBL,可以只应用碳青霉烯类进治疗;如果产生碳青霉烯酶,则应用多粘菌素、替加环素或磷霉素进治疗。

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Osmosis-微生物

In this case, it can be treated with cephalosporins, aminoglycosides, fluoroquinolones, and carbapenems.

在这种情况下,可以应用头孢菌素类、氨基糖苷类、诺酮碳青霉烯类药物进治疗。

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医学百科 The Medicine Book (Big Ideas Simply Explained)

Quinolones, another class of antibiotics, use the third method of attack, preventing the bacteria from reproducing their genetic material so they cannot multiply.

另一类抗生素诺酮类采用第三种攻击方法,阻止细菌复制其遗传物质,从而无法繁殖。

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Huberman Lab

If an individual is on a fluoroquinolone, there's a risk for, you hear a lot about these Achilles injuries.

如果一个人在服用诺酮类药物,会有跟腱受伤的风险, 这方面的报道很多。

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医学英语 心内科

But most importantly antipsychotics and certain antibiotics such as macrolides and quinolones.

但最重要的是抗精神病药和某些抗生素,如大环内酯类和诺酮类。

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