The main equipment here is a thermal cycler system for nucleic acid amplification (PCR, quantitative fluorescence detection or common).
主要
器就

扩增
循环
(PCR
,
时荧光或普通的)。
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集 So both an MYCN amplification or ALK gene fusion, where the oncogene is " turned on, " or a PHOX2B and chromosome 1 and 11 deletions, where tumor suppressor genes are " turned off, " can potentially cause uncontrolled cell growth.
因此,MYCN基因扩
或ALK基因的融
,即致癌基因被激活,或PHOX2B与1号、11号染色体缺失,即抑癌基因的失活,都可能导致细胞生长不受控制。
集
集
集
集
This process of adding more repeats is called repeat expansion and it happens way more in the production of sperm than of eggs, so both anticipation and new disease alleles generally happens when the father is the affected parent.
这种序列重复
加称为重复序列扩
,精子产生时发生异常的几率比卵子高,因此当父亲为受累个体时,会发生早现现象和新的疾病等位基因。