Even when no stigma attaches to the drugs involved, most clinical trials end in failure.

即使这种药物没有任何不光彩的地陷，那么大多数的临床实验还将败告终。

Have I done stuff for money that I'm not proud of? Yeah, sure.

我是否为了钱做了不光彩的事？当然。

If a person is under a cloud, they are thought to have done something bad or dishonorable.

如果一个人“under a cloud（被嫌弃/被贬低）”，那这个人就做了什么坏事或者不光彩的事情。

Protect Your Image We all do things that we're not proud of.

保护自己的形象我们都做一些不光彩的事。

I can imagine no more dishonorable act by a president.

我不能想象一位总统有更不光彩的行为。

The spokesman blamed the negative role those countries have played.

发言人指责这些国家扮演角色了不太光彩的角色。

Now I am left to a lonely and dishonoured age.

现在我落到了要过孤独和不光彩晚年的地步。

To survive, I...I had to do a bunch of stuff that I'm not proud of.

为了生存，我...我不得不去做些不光彩的事情。

People who change jobs are often considered quitters, and that is seen as dishonorable.

换工作的人通被认为是半途而废的人，这被认为是不光彩的。

God knows I've done some stuff I'm not proud of.

我也做过一些不光彩的事。

You know things about me that aren't good.

你也知道我一些不光彩的事。

You said you wanted to know me, even the bad things.

你说你想了解我，包括不光彩的事。

It would be dishonorable for me to say...

我说出来是不光彩的。

In the US, smoking carries a stigma.

【stigma】在美国，吸烟是不光彩的。

Furious with himself for having given away a discreditable secret, he vented his rage on Bernard.

他因为透露了一个不光彩的秘密对自己生了气，却把怒气发泄到伯纳身上。

Meanwhile, all I've done since then is think about it- the terrible things you've done.

于此同时，从那之后我一直在想它——你做的那些不光彩的事。

Or does a dollar earned honestly have a different value than a dollar with a sketchy history?

靠正当劳动挣取的一美元与有不光彩历史的一美元价值不同吗？

Whether it's your friend's term paper or words of a well-known author, plagiarism is cheating and dishonest.

无论你占用的是你朋友的学期论文还是某位名家的言论，都被视为剽窃，这是作弊，是不光彩的。

Wha...? What do you wanna know? Have I done stuff for money that I'm not proud of?

什么？你想听到什么答案？我是否为了钱做了不光彩的事？

So shall those blots that do with me remain without thy help by me be borne alone.

这样一来，我身上不光彩的疤痕，不劳你分忧，我自当独自担承。