Filariasis happens when one of these nematodes gets in the lymphatic system and causes a bit of fibrosis, which creates a physical blockage that obstructs the normal flow of lymph.
One of the most common global causes of lymphedema is filariasis, an infection with nematode parasites, which are tiny worms; the most common species are: Wuchereria bancrofti, Brugia malayi, and Brugia timori.