Severe hypoxia leads to high-output cardiac failure and massive hepatosplenomegaly, resulting in edema all over the body, called hydrops fetalis.

重度缺氧会引起高输量性心力衰竭和巨大肝、脾，进而性水肿，称水肿胎儿。

This causes generalized edema which is often seen in the legs, face and hands; pulmonary edema which can cause cough and shortness of breath; and cerebral edema which can cause headache, confusion, and seizures.

性水肿，主要累及下肢、面部和手部；以及肺水肿，造成咳嗽、气促；还有脑水肿，造成头痛、意识不清和癫痫发作。