Your insulin even that helps regulate your metabolism is turned upside down.

甚至使调节代谢胰岛素发生功能紊乱。

People with zinc deficiencies have severe immune dysfunction, and many die from infections.

缺乏锌人有严重免疫功能紊乱，并且很多死于感染。

Muscular dystrophy is actually a group of disorders, all of which are caused by genetic mutations.

肌营养不良是一系列由于基因突变功能紊乱。

Turns out that volunteers who ate white bread had more Lactobacillus, a type of bacteria that wards off digestive disorders.

结果显示摄取白面包志愿者们含有更多乳酸杆菌，这种菌可以有效地抑制肠道功能紊乱。

Boys who grow up without fathers are more likely to have trouble forming lasting relationships, creating a cycle of male dysfunction.

在没有父性角色家男孩，将更可能不能处理好久关系（如夫妻关系）以至于形成新单亲家，由此形成一个男性功能紊乱死循环。

And that ultimately causes death of tissue and disruption of bodily functions, neurologic function.

最终导致组织死体功能、神经系统功能紊乱。

Today we discuss how metabolic function and dysfunction impacts our health.

今天我们将探讨代谢功能及其紊乱如何影响我们健康。

Is in the absence of any apparent or suspected endocrine dysfunction, right?

是在没有明显或可疑内分泌功能紊乱情况下，对吧？

High levels of cortisol also inhibit the secretion of gonadotropin- releasing hormone from the hypothalamus, which messes up normal ovarian and testicular function.

高水平皮质醇会抑制促性腺激素分泌，即下丘脑分泌释放激素，导致卵巢睾丸功能紊乱。

In some cases leading to overproduction of too many cells or disruptions in the functions of cells.

在某些情况下，这会导致细胞过度增殖或细胞功能紊乱。

After these initial symptoms, late-stage syphilis was known to cause organ damage, heart and brain disorders, and even blindness.

在出现这些初始症状后，众所周知，晚期梅毒会导致器官损伤、心脏脑功能紊乱，甚至失明。

So what we see is that with a disrupted gut, we see abnormalities in mood, in cognition, in memory.

因此，我们观察到是，当肠道功能紊乱时，情绪、认知记忆方面会出现异常。

Apparent endocrine dysfunction, okay, in your mid-20s.

明显内分泌功能紊乱，好嘛，在你二十多岁时候。

Neurological disorders may occur if this communication between cells is disrupted through viral infections, drug use, ageing or genetic factors.

神经功能紊乱可能会因病毒感染、药物使用、衰老或遗传因素导致细胞间通信中断而发生。

Depression and other mental health disorders, certain kinds of cardiovascular disease, metabolic dysfunctions, even allergies and asthma to some extent.

抑郁症及其他精神健康问题、某些心血管疾病、代谢功能紊乱，甚至在某种程度上，过敏哮喘。

There have been research showing other health risk associations with diet soda, such as increased blood pressure, gut dysfunction, metabolic syndrome, cancer and increased risk of stroke.

有研究表明，无糖汽水还有可能导致其他健康问题，比如血压升高、肠道功能紊乱、代谢综合征、癌症中风风险增加等。

Within that group, dystrophinopathies are the most common, which includes Duchenne muscular dystrophy, or DMD, and Becker muscular dystrophy, both of which result from mutations in the dystrophin gene.

这些功能紊乱中，营养不良疾病是最常见，包括Duchenne型肌营养不良（DMD）Becker型肌营养不良（BMD）；这二者都是由抗肌萎缩蛋白基因突变导致。

Part of his weakness in trying to manage a dysfunctional company was his desire to please other people, one of many traits that he did not share with Jobs.

他正试图管理一家功能紊乱公司，而他管理存在一个弱点，那就是他总想取悦别人，这个问题在乔布斯上并不存在。

But I would also like to mention that this impairment of these other cell types and other processes in the brain can also impact the strength of the gamma waves.

但我也想说其他细胞受损脑其他功能紊乱也会反过来影响伽马波强度。

With pelvic floor dysfunction, stool becomes difficult to eliminate from the rectum because of tightened pelvic floor muscles, or due to a pelvic organ prolapse, usually through childbirth or aging.

而骨盆底功能紊乱时，粪便变得很难从直肠中排出。原因可能是盆底肌过分紧张或者骨盆器官下垂。