And these are women who are undergoing in vitro fertilization, IVF, so we're also looking at their follicular fluid-so the fluid around the eggs that we get at the time of the egg retrieval.
There is some evidence that men are more attractive to women when they are in the follicular phase of their menstrual cycle, and their testosterone levels are at their highest.
The body will respond by producing more follicle-stimulating hormone (FSH) and luteinizing hormone (LH) than normal, since these hormones stimulate estrogen secretion by the ovaries.
The FSH drives that one lucky follicle to keep growing, by triggering the follicle itself to secrete its own estrogen hormones, which locally signal the follicle to mature even more.
In a graafian follicle, a central cavity called the antrum forms within the follicle, and the granulosa cells secrete a nourishing fluid for the primary oocyte directly into that antrum.
The LH gets to work on the oocyte that's been dormant inside the follicle, and triggers it to finally start dividing again — getting it to complete meiosis I and move on to metaphase II.
LH 开始作用于卵泡内休眠的卵母细胞,并触发它最终再次开始分裂——让它完成减数分裂 I 并进入中期 II。
The second stage of follicular development begins for a few lucky primary follicles with the first menstrual cycle in puberty, and a few more primary follicles go into the second stage with each subsequent menstrual cycle.
The follicle-stimulating hormone lives up to its name by stimulating the growth of a follicle — but only one: the one that happens to be furthest along in development at the time.