When your brain gets sloshed and squished, twisting forces happen down on the smallest level, deforming and tearing nerve cells, and damaged neurons can't don't goodly communicate good.
Now, the sudden gush of blood through the collateral vessel stretches its walls and deforms the endothelial cells, which stimulates the production of growth factors like the vascular endothelial growth factor, or VEGF, from the vessel wall.