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The expression of interleukin-5 (IL-5) has been correlated with the maturation and differentiation of eosinophils, and is considered to be a cytokine responsible for allergic inflammation.

IL-5与粒细胞成熟和分化密切相关, 是炎症关键细胞因子。

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This is the appearance of normal bone marrow smear at high magnification. Note the presence of an eosinophilic myelocyte, a basophilic myelocyte, and a plasma cell.

高倍镜下正常骨髓涂片,可见一个粒细胞,一个粒细胞和一个浆细胞。

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Osmosis-泌尿

This inflammation is caused by infiltration of immune cells, like neutrophils and eosinophils, which then cause inflammation.

这种炎症是由于免疫渗入导致的,比如,从而造成炎症。

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Osmosis-解剖与生理

Unlike neutrophils and eosinophils, basophils are non-phagocytic.

不同的是,并不具备吞噬功能。

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2017级专外有声

There are five different types of leukocytes: three types of granulocytes (eosinophil, basophil, and neutrophil) and two types of agranulocytes (monocyte and lymphocyte).

三种)和两种无(单核和淋巴)。

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Osmosis-心血管

Loffler syndrome, where eosinophils accumulate in the lung tissue, can also affect the heart tissue, called Loeffler endocarditis or sometimes loeffler endomyocarditis.

Loffler综合征:聚集在肺组织,也可以累及心脏组织,这种情况叫做Loeffler心内膜炎,有时也叫Loeffler心内膜肌炎。

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Osmosis-解剖与生理

Now, in comparison to neutrophils, eosinophils and basophils are far less common.

要不常见得多。

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经济学人-科技

The researchers could do this because they identified a distinctive antigen on the surface of the eosinophils: a receptor for the signalling molecule interleukin-5.

研究人员之所以能做到这一点,是因为他们发现了表面的一种独特抗原:信号分子白介素5的受体。

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Osmosis-心血管

In this case, eosinophils accumulate in the endocardial layer of the heart tissue, causing inflammation and endocardial fibrosis, making it stiffer and again less compliant.

在这类病例聚集在心脏组织的心内膜层,导致炎症和心内膜纤维化,让其更加僵硬、顺应更差。

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Osmosis-呼吸

The mucus may also contain Charcot-Leyden crystals which are shaped like needles and are formed by the breakdown of eosinophils.

黏液也可能含有一些针状的Charcot-Leyden晶体,由分解形成。

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Osmosis-解剖与生理

Eosinophils are also phagocytic, and they're best known for fighting large and unwieldy parasites because eosinophils are much larger than neutrophils and have receptors that are specific for parasites.

同样具有吞噬作用,它们以对抗巨大而笨重的寄生虫而闻名,因为要比大得多而且有专门针对寄生虫的受体。

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经济学人-科技

To design a therapy that could target eosinophils, the Chinese group, led by Peng Min at Tsinghua University in Beijing, added a CARprotein to the T-cell surface tailored to recognise this specific antigen.

为了设计一种可以针对的疗法,由清华大学彭敏领导的国研究小组在T表面添加了一种专门用于识别这种特定抗原的CAR蛋白。

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Osmosis-泌尿

Early symptoms include oliguria and eosinophiluria, which is eosinophils in the urine, but also general symptoms like a fever and a rash.

早期症状包括少尿和尿,即尿液存在,但也有发烧和皮疹等一般症状。

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Osmosis-呼吸

IL-5, on the other hand, activates eosinophils which promote an immune response by releasing more cytokines and leukotrienes.

另一方面,IL-5激活,通过释放更多的因子和白三烯来促进免疫反应。

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Osmosis-解剖与生理

They stain blue with the dye hematoxylin, and like eosinophils they can be helpful at combating large parasites but also cause inflammation in asthma and allergy responses.

它们用苏木素染色后呈蓝色;像一样,它们可以助力奋战寄生虫,但也会引哮喘和过敏反应。

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Osmosis-解剖与生理

Those cytokines start the inflammatory process by making blood vessels leaky and attracting nearby eosinophils, basophils, and mast cells, which release their own cytokines and granules amplifying the inflammation.

这些因子将启动炎症过程:通过使血管渗漏并吸引附近的和肥大;这些集结的释放各自的因子和颗粒,放大炎症反应。

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Osmosis-解剖与生理

Eosinophils stain pink with the dye eosin - which is where they get their name.

用伊红Eosin染色呈粉红色,也就是它英文名Eosinophil的来源。

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豪斯医生一

That wouldn't give you an elevated eosinophil count.

脉管炎不会导致增加。

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2017级专外有声

Eosinophils take up a red acidic dye called eosin; their main function is to detoxify foreign proteins, especially those causing allergic reactions.

吸收一种叫做伊红的红色染料;它们的主要功能是解除外源蛋白质,特别是那些引过敏反应的蛋白质的毒

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