Peak concentrations and gradients for gentamicin aried considerably between animals, likely resulting from ariations in round window membrane permeability and rates of perilymph flow.
In the drug tolerance examination, the Vibrio parahaemolyticus were very semsitive for the four drugs, the SMZ, cefamandole, chloromycetin, gentamicin and not sensitive for the ampicillin, cefalotin.
One particular combination of widely used antibiotics—gentamicin, then cefuroxime, then gentamicin again, and so on—looks like it could hold the bugs at bay indefinitely.